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Adolescents typically experience dramatic physical changes, usually become more independent decisionmakers, and often engage in risky behaviors. As a result, they require health services tailored to their unique needs. Several CHIPRA quality demonstration States are working with participating providers to enhance their ability to deliver such services and improve the overall quality of health care for adolescents. Specifically, North Carolina and Utah are facilitating adolescent-focused quality improvement (QI) collaboratives for primary care practices, and Colorado and New Mexico are providing support and coaching to school-based health centers (SBHCs) serving adolescents. This Evaluation Highlight describes barriers these States encountered in their efforts to improve care for this population, identifies strategies to address these barriers, and suggests actions States could take to enhance adolescent health care.