Preventing Autism Epidemic by Reducing Inflammation, Oxidative Stress, and Acetaminophen Exposure

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our children our futures
By Dennis D. Embry, Ph.D.

autism2In much of the developed world, autism appears epidemic—but not caused by vaccinations. Three variables are at work, which bear explanation for my readers. My essay summarizes a must read medical article entitled: The role of oxidative stress, inflammation, and acetaminophen exposure from birth to early childhood in the induction of autism.[1] You can read a summary by the first author that is linked to the full medical article. Consider the tripod of causes:

In their paper, Parker and colleagues put all the mechanisms together—weaving a logical and coherent explanation of the autism epidemic. More importantly, we can almost certainly prevent many cases of autism by withdrawing almost all use of acetaminophen for pediatric patients, especially because there are other options with less risk. Their paper describes how a study might be conducted to clarify this further. In the meantime, most pediatric uses of acetaminophen are unnecessary and contraindicated, like giving a dose before shots or low-grade fevers.

This finding raises a false-flag of blaming parents for autism, which some may be prone to do. That is not the case here. We cannot undo the past causes of autism, but we do have sound scientific for avoiding the use of acetaminophen/paracetamol among children, and probably prenatally to reduce the risk of autism spectrum disorders for hundreds of thousands of children. That is good news for children, their families and schools.

1. Parker W, Hornik CD, Bilbo S, Holzknecht ZE, Gentry L, Rao R, Lin SS, Herbert MR, Nevison CD: The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism. The Journal of International Medical Research 2017, 45(2):407-438.
2. Good P: Did acetaminophen provoke the autism epidemic? Altern Med Rev 2009, 14(4):364-372.


embryDennis Embry, President/Senior Scientist at PAXIS Institute – Dennis D. Embry is a prominent prevention scientist in the United States and Canada, trained as clinician and developmental and child psychologist. He is president/senior scientist at PAXIS Institute in Tucson, Arizona. Dennis Embry serves on the scientific advisory board for the Children’s Mental Health Network, the board of the Federation of Families for Children’s Mental Health, and the National Advisory Council of the U.S. Center for Mental Health Advisory Council. 

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